What is the difference between peripheral arterial disease and peripheral venous disease?

Artery vs vein: think of one (Periph artery disease) as problems with the vessels in charge of delivering blood, oxygen. and nutrients to the tissues and the other (peripheral venous disease) as problems with the vessels in charge of returning that blood to the heart.

Differences: Peripheral arterial disease refers to the arterial blood which is the oxygenated blood from your heart which gets pumped throughout your body. Disease in these blood vessels inhibit the amount of oxygen getting to your tissues. Peripheral venous disease refers blood vessels returning deoxygenated blood to the heart and lungs. The veins that typically are the ones that bulge out (varicose veins).