Should i smoke a bit of weed for the first time? is it safe?

Should you?????: I am not sure why you think a doctor can (or even should) answer that question. If you have managed to reach the age of 32 without using marijuana, I would strongly recommend you keep it that way. It is, firstly, still illegal and people who are naive about how to get it are often the people who get into trouble when they try, and then have a criminal record. It also can cause anxiety/panic.