A member asked:

Can you take benadryl (diphenhydramine) and nyquil at the same time?

A doctor has provided 1 answer
Dr. Larry Xanthopoulos answered

Specializes in Pediatrics

Not best idea: Nyquil has an antihistamine in it already, and benadryl (diphenhydramine) is an antihistamine so you run the risk of overdosing on the antihistamine component. This may cause drowsiness, dryness and can possibly effect respiratory drive. So, not a good idea to take both together.

Answered 1/29/2020

3.6k views

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