Diagnosed with giant liver hemagioma size of grapefruit read online that could cause anemia because it sequesters red blood cells is that true ?

Yes: One of the problems of giant hemangiomas of the liver is that there is a tendency to rupture which could result in massive blood loss. I would expect that if present in the rt. location (lobe) of the liver it is best handled by resection. Otherwise interventional radiology should do a hepatic angiogram and thrombose the arterial segment feeding the lesion.

Yes, but: Brief answer is yes, however other causes of anemia must be ruled out before attributing anemia to this hemangioma !