For the past 3 weeks i have been talking 150mg effexor (venlafaxine) xr. if i cut back tomorrow to 75mg xr will i get any withdrawal? i felt the 150 made me anxious

Effexor (venlafaxine) is not ap- : proved for treatment of Bipolar Depression. Anti- depressants can increase risk of a mixed/ manic episode if used without a mood-stabilizer. Combining Effexor (venlafaxine) & Trazodone increases risk of Serotonin Syndrome. See http://www.drugs.com/drug-interactions/effexor-xr-with-trazodone-2296-1523-2228-0.html?consumer=1. Ask your doctor about 37.5 mg. decrements in dose of Effexor (venlafaxine) & the other issues.