Can zoloft (sertraline) affect eyesight?

Yes but ....: more often than not the eye problems are due to something else. Best have the eye doctor have a look. (refraction, tonometry and a good look at the back of the eye ) If then it is thought that the medication may be contributing, the prescribing physician should be made aware and allowed to participate in any proposed change in medication.

Possibly: Per Drugs.Com there is potential for: "Common (1% to 10%): Abnormal vision, visual disturbance. Uncommon (0.1% to 1%): Abnormal accommodation, conjunctivitis, eye pain, mydriasis. Rare (less than 0.1%): Abnormal lacrimation, angle-closure glaucoma, anterior chamber eye hemorrhage, diplopia, exophthalmos, photophobia, ptosis, scotoma, visual field defect, xerophthalmia Postmarketing reports: