Tell me the effects of the drug "penicillamine-d" on long term usage?

Anemia, kidney, etc: Penicillamine has been used to treat rheumatoid arthritis for over 50 years. It has significant toxicity. The most frequent and severe are bone marrow suppression leading to anemia, low white counts, and low platelet count, and kidney damage which may be irreversible. It is a chelating agent which helps remove toxic buildup of copper and other heavy metals. Not really used anymore for arthritis.