A member asked:

Why is benadryl (diphenhydramine) more effective for hives than allegra?

A doctor has provided 1 answer

Antihistamines: some hives respond better to first generation antihistamines, but in general if the hives are chronic, they are better suppressed with a second generation antihistamine, such as Allegra (fexofenadine) or Zyrtec as they are longer acting and less sedating

Answered 9/1/2014

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