Changing insulin from humalog (insulin lispro) to novolog - any effect?

Congratulations: Great move. Well, NovoLog is quicker acting but also quicker getting out of your system. So make sure you eat as soon as you inject. As with any insulin, proper close titration is necessary to avoid hypoglycemia and wild fluctuations in your sugar levels. Overall, best short acting Insulin on the market at present, and the most physiologic.