A member asked:

Does it matter if you take 400 mg plaquenil (hydroxychloroquine) at once vs 200 in the morning and 200 in the afternoon?

2 doctors weighed in across 2 answers

Either way is fine : It can be taken 400 at one time or 200 twice a day

Answered 9/29/2017

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Probably not, but: Since Plaquenil (hydroxychloroquine) has such a long half life it probably doesn't matter, but if you are like most people it is easier to remember to take pills once a day than twice a day. Why take the risk of missing doses?

Answered 7/27/2014

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