A member asked:

I wanted to know is celiac a chromosome or point mutation?

4 doctors weighed in across 2 answers
Dr. Michael Rupp answered

Specializes in Allergy and Immunology

Neither: Celiac disease is caused by an antibody made by your own body attacking the lining of your small intestine. It is not a single gene or chromosomal defect.

Answered 2/16/2016

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Neither: The main risk factor that must be inherited is a specific immune sensing molecule but it is not mutated. There are other regions of genetic risk that are being worked out.

Answered 11/27/2017

3.6k views

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