A member asked:

I take tri-sprintec and i'm getting really bad mood swings and physical symptoms. i used to be on ortho lo and no issues. what's the difference?

A doctor has provided 1 answer

Higher estrogen dose: Tri-Sprintec and Ortho Tri-cyclen Lo have exactly the same progresterone (Norgestimate) but Tri-sprintec has 35 mcg of Estradiol and Ortho Tri-Cyclen Lo only has 25 mcg of . Estradiol. The symptoms may be due to the slightly higher estrogen dose.

Answered 6/26/2015

3.9k views

Thank

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