Higher estrogen dose: Tri-Sprintec and Ortho Tri-cyclen Lo have exactly the same progresterone (Norgestimate) but Tri-sprintec has 35 mcg of Estradiol and Ortho Tri-Cyclen Lo only has 25 mcg of . Estradiol. The symptoms may be due to the slightly higher estrogen dose.
Answered 6/26/2015
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