Side effects from decadron (dexamethasone) and depo-medrol medicines?

Many: These are corticosteroids. With most medications, there are possible side effects; with these steroids, they are guaranteed. It is only a matter of which ones will occur. From osteoporosis, bone fracture, skin tearing, death. They can be critical to preserve life, but should be used with careful consideration, as to whether other safer medications would be more appropriate.