U.S. doctors online nowAsk doctors free
A 34-year-old member asked:

What is the difference between allegra (fexofenadine) and flonase for allergy relief -take one or both?

1 doctor answer3 doctors weighed in
Dr. John Klimas
Allergy and Immunology 49 years experience
Flonase better: Allegra is an atihistamine and is helpful for itchiness, sneezing and a runny nose, not helpful for congestion. Flonase, an intranasal steroid covers all these symptoms plus congestion. Head to head studies comparing Flonase to antihistamines, singulair, (montelukast) or sudafed showed that Flonase beat them all. I usually suggest daily Flonase and adding an antihistamine on as needed or supplemental basis.
Dr. Robert Ramirez
Allergy and Immunology 19 years experience
Nasal steroids should always be no. 1 for the reasons above. Everything else could be considered a "back up" for the nasal steroid.
May 1, 2012
Last updated May 10, 2018


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.