A member asked:

What is the probability that a woman whose brother has duchennes disease will herself have an affected child?

A doctor has provided 1 answer

1 in 8: Well, if grandma is a carrier, the woman herself has 50% chance of being a carrier, and if she is, 50% of her daughters will be carriers and 50% of her boys will be affected - so 1 in 8 for a child in general, 1 in 4 for a boy.

Answered 7/5/2012

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