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A 23-year-old male asked:

Is acetaminophen less irritating to stomach and intestines than ibuprofen?

1 doctor answer2 doctors weighed in
Dr. Nayana Trivedi
Internal Medicine 40 years experience
Yes: Non steroidal anti inflamtory medicine(nsaid) like ibuprofen, advil, aleve, naproxen, commonly available drugs for pain relief can irritate the gastric mucosa and can cause gastritis even the bleeding ulcer. Therefore it is not advisable to take it on empty stomach.Where as tyleno (actamenophen) is not nsaid.
Dr. Paul Grin
Dr. Paul Grin commented
Pain Management 37 years experience
Acetaminophen produces fewer gastric problems than aspirin, does not interfere with the clotting mechanism, and is generally well tolerated.
May 5, 2014
Last updated May 5, 2014

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