A 27-year-old male asked:
I'm on testosterone therapy, i keep hearing that some of it converts to estrogen. does it convert to estrone or estrodiol or estriol or all three?
1 doctor answer • 2 doctors weighed in
Urology 45 years experience
Estradiol: Estradiol is synthesized via aromatase from testosterone. Estrone is synthesized via aromatase from androstenedione. Estriol is synthesized from both Estradiol and estrone. Estradiol is ~10 times as potent as estrone and ~80 times as potent as estriol in its estrogenic effect. In some men on t replacement, too much t is converted to Estradiol and may require a drug like Arimidex (anastrozole) to block.
4.1k viewsReviewed >2 years ago
Last updated Jun 25, 2014
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.