Any insights for why i colon cleansers don't work for me?

It depends.: In reality, colon cleansers do not work for anyone, since they are unnecessary. The colon does a fine job of cleaning itself out, just in the process of having bowel movements. There is not an accumulation of toxins in the colon, so colon cleansers or unnecessary. If you are actually referring to the need for laxatives, send us another note or use HealthTap Prime. Hope that helps.