No: No calluses are generally limited to the skin and subcutaneous tissue. They are not related to any bone deformity. If calluses are not kept clean they may not heal which may eventually cause a local infection. And worst case scenarios this infection may spread to the bone and cause osteomyelitis which is the infection of the bone. This could be complicated specially in diabetic patients and may require amputation of the bon.
Answered 4/12/2014
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