A member asked:

Can you take 100mg of doxycycline and 25mg of zoloft (sertraline) together?

A doctor has provided 1 answer
Dr. Linda Callaghan answered

Specializes in Addiction Medicine

Probably not.: There has been reported side effects from the combination among them are headaches, difficulty breathing, anemia, back pain even osteonecrosis of the jaw and anxiety. However, the people who had these drug-drug interactions took a larger dose of zoloft (sertraline) and the Doxycycline for several days so I am not sure whether the doses or duration have played a factor.

Answered 12/19/2017

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