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A 45-year-old member asked:

Can you tell me is levetiracetam better than phenobarbital?

1 doctor answer1 doctor weighed in
Dr. Jefferson Chen
Neurosurgery 35 years experience
May vary: The choice of Keppra (levetiracetam) vs Phenobarbital for seizures may be related to the type of seizure. Keppra (levetiracetam) is a newer anti-epileptic drug than Phenobarbital and easier to dose correctly. Phenobarbital requires frequent blood tests to check the levels. Phenobarbital, in general, is more sedating and may affect cognitive function more than the keppra (levetiracetam). Check with your neurologist about the specifics.
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Last updated Jun 30, 2014


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