A member asked:

Help please? what is the difference between type i hypersensitivity to type ii?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Type I is immediate: hypersensitivity reactions, involves IgE with histamine and other mediators release from mast cells, while type II is cytotoxic hypersensitivity reactions involving IgG or IgM bound to cell surface antigens, with subsequent complement (a protein in the blood) fixation, there are also type III and type IV reactions, type I reactions are responsible for immediate allergic symptoms to foods or drugs

Answered 1/31/2015

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