Does chemotherapy affect eyesight?

It can, yes.: Most effects on the eyes are minor and temporary, such as dry eyes, watery eyes, and irritation (called "conjunctivitis"); but chemo can cause more serious problems, like cataracts. You should notify your oncologist immediately if you notice any change at all in your eyesight.

Some: Transiently many patients will have some trouble focusing; somewhat like when ones eyes are tired. Steroids which are commonly used with chemotherapy drugs can increase cataract formation, which used to be a leading cause of poor vision, but now can almost always be fixed quite easily.