How long do they have to wait after their last dose of codeine for their first dose of tramadol? they are 14 male

Six hours: I suggest six hours because the half-life of Codeine is somewhere between one and three hours. That means that half of your dose of Codeine is metabolized in somewhere between one and three hours and half of the residual is metabolized in another three hours. Usually in the young healthy person i would expect the metabolism to be a lot quicker than any older person. So by six hours in a 14-year-ol.