Is it safe to smoke marijuana while taking prozac (fluoxetine)? also am i able to have a drink here and there? i just want to know what's safe and what isn't.

No, not safe: No, it's not safe to combine marijuana or alcohol with prozac (fluoxetine).

Talk to your doctor: Marijuana can increase depression, anxiety and social anxiety in particular, so you may be playing both ends against the middle here. Alcohol is also a depressant, and you are 18 years old. Marijuana is particularly bad for brains that are still growing and maturing. If a doctor is treating you for depression you have an obligation to let them know if you are drinking or using pot.