Is taking hydrocodone worse than smoking pot or drinking?

Depends: How much hydrocodone? And how much smoking pot, and how much drinking? Occasional use of recreational pot, like social drinking, (1-2x/week) with modest doses of drug causes little harm in most people, but it depends on whether you have liver disease, panic attacks, family history of alcoholism etc. Regular use of hydrocodone produces physical dependency, but little in the way of organ toxicity.