A member asked:

Need a simple explaination for this. what is marfan syndrome?

A doctor has provided 1 answer

Genetic disease: Marfan syndrome is a genetic disease affecting the "connective tissue" in the body, with effects in various organ system. True Marfan syndrome is caused by a mutation in the fibrillin-1 gene, located on chromosome 15. Inheritance is autosomal dominant, and it appears that about 25% are spontaneous mutations. Serious effects on the structure and function of the heart, aorta, eyes, and bones.

Answered 6/6/2019

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