A member asked:

Are p63 and ttf1 used to distinguish small cell lung cancer from non small cell lung cancer? or are they used for more specific distinctions?

A doctor has provided 1 answer
Dr. Richard Mcgee answered

Specializes in Medical Oncology

Yes: P63 is positive in lung squamous cell cancers usually while ttf1 (thyroid transcription factor) is positive frequently in lung adenocarcinomas. Both should be negative in small cell lung cancers usually.

Answered 4/24/2015

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