Can cocaine use cause swollen lymph nodes in the neck?

No: I would consider other causes. See your doctor.

Maybe: Definitely see your doctor, as soon as possible. Are you injecting cocaine? In any case, tell the doctor that you are using Cocaine and how you are using it.

No: Cocaine or other drugs (even sniffed) would not do this. If you have a sore throat, that's probably the cause and both this and the enlarged nodes should clear pretty soon on their own. If not, and especially possible enlarged nodes persist more than 1-2 weeks, see a doctor and get it checked out.

Depends: It is unlikely that the cocaine in and of itself would cause lymph nodes to swell (lymphadenopathy); however, whatever other substances are within the administered drug could very well do so. Use of cocaine is incredibly dangerous, not only for the well known effects and addiction issues, but also because of the co-administered materials "cut" with this drug of abuse.