A member asked:

Effexor (venlafaxine) vs cymbalta, currently effexor (venlafaxine) 225, suffering from somnolence, fatigue.cymbalta in such case?best regards for your care.

8 doctors weighed in across 4 answers

other options: Both meds are serotonin norepinephrine reuptake inhibitors therefore will have similar side effect profiles. There are other medications available for the tx of depression. I noted you were on ritalin (methylphenidate). If you have an add diagnosis often times you will experience opposite effects from meds. For ex. Stimulating meds will cause fatigue and visa versa. Ck with your dr. For options.

Answered 3/23/2016

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Effexor (venlafaxine) vs Cymbalta: Effexor (venlafaxine) is known for causing daytime sleepiness. This is much less common with Cymbalta even at doses of 120 mg ever morning.

Answered 4/8/2018

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Can be the cymbalta (duloxetine): Cymbalta (duloxetine) I have observed can produce fatigue. Changing to a different medication or reducing the dose can reverse this. Not sure changing to a different med on the same class would make a difference. Depending on your reason for this medication, a different class medication may be indicated.

Answered 3/23/2016

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Dr. Nicole Carlberg answered

Specializes in Psychiatry

Psychopharmacology : There are many different small details taken into account when considering medication choices for patients. Effexor (venlafaxine) and Cymbalta have some similarities. From your brief description it appears as though an appnt is needed with your dr. Make a list of concerns, questions. Bring in your meds, talk about the changes you might want to consider to target your concerns. Schedule extra time if needed.

Answered 3/23/2016

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