Q: hx of rectal ca sp lar, cea 4m interval rise from <0.5 to 2.4, bilirubin 0.4, alkaline phosphatase 46, alt 46, but high ast 79. what's the cause?

LIVER PROBLEM: No evidence with the tests that there is recurrent rectal Ca. The AST or SGOT suggests there is some form of liver damage that should be evaluated by scan and possible liver biopsy.

Q: calcium high at 10.7, alkaline phosphatase very low at 10. negative parathyroid, not anemic, celiac, copper level is normal. what could be the cause?

Watch it: You may have hypocalciuric hypercalcemia, with probably isn't worth the workup as it's not something worth treating. I trust you're not taking a thiazide or dolomite pills, or overdoing milk / antacids. Unless you also have a low albumin, this is unlikely to impact your life. Low alk-phos is never worrisome. Best wishes.

Q: 10 days post-op abdominal hysterectomy and ovary removal. bloodwork today, alkaline phosphatase is high 139. still taking pain meds. cause for concern?

Alk Phos: The answer would depend on why your doctor checked your Alkaline Phosphatase level. Typically it is done looking for gallbladder, liver and done disorders. Check with your doctor to see why the test and was done and how it can be interpreted given your current clinical scenario.

Question 1

what are the causes for elevated alkaline phosphatase?

Accepted Answer

ALP: Paget's disease, bone fractures or cancers.

Question 2

what condition might cause an elevated alkaline phosphatase?

Accepted Answer

Many causes: Most commonly released from the liver / bile ducts in addition to bone.

Question 3

high alkaline phosphatase but everything else normal. had a total replacement 1month ago. is this the reason or what else could be?

Accepted Answer

Varies: Alkaline phosphatase is an enzyme usually associated with bone turnover.  If it is mildly elevated and normalizing, then it could potentially be related to your surgery.  If it is highly elevated, then there may be other considerations, Paget's disease being just one possible consideration.

Question 4

what could cause alkaline phosphatase levels to steadily increase over a period of years, now at an elevated level?

Accepted Answer

Alkaline phosphatase: Causes for elevated Alk phos: biliary obstruction stone, tumor, stricture; autoimmune biliary cirrhosis; liver infiltrates do to granuloma, fatty liver, amyloidosis, sarcoidosis, malignancy; meds like estrogen, chlorpromazine, erythromycin ; viral hepatitis; bone diseases: Paget's, osteomalacia, mets to bone, PTH disease, vitamin d def, fracture

Question 5

does elevated alkaline phosphatase cause bone pain?

Accepted Answer

No: Alkaline phosphatase is known as a "marker" of increased bone (or liver) metabolism. It is contained in bone (and liver) so it will be elevated when bone is being broken down or resorbed as in paget's disease or bone cancer.  It doesn't cause bone pain per se, but whatever is causing the bone to break down in the first place (e.g. Paget's disease or bone cancer) is the cause of the pain.

Question 6

what causes bone pain and elevated alkaline phosphatase in women?

Accepted Answer

Several conditions: You could have the condition called paget's disease, however they are some other diseases that could produce elevated alkaline phosphatase such as liver cirrhosis of obstruction of the biliary tract, some medications and some type of cancers.Proper testing is necessary for proper diagnosis.

Question 7

i am having low and high alkaline phosphatase result. ultrasound and x-ray report shows a healthy liver. what could be the cause?

Accepted Answer

Many sources: Alkaline phosphate is high due to multiple reasons. They get high due to problem in liver, bone or intestine. It's unclear if your level gets to normal. It will be wise to discuss with pcp.

Question 8

hx of rectal ca sp lar, cea 4m interval rise from <0.5 to 2.4, bilirubin 0.4, alkaline phosphatase 46, alt 46, but high ast 79.  what's the cause?

Accepted Answer

LIVER PROBLEM: No evidence with the tests that there is recurrent rectal Ca.  The AST or SGOT suggests there is some form of liver damage that should be evaluated by scan and possible liver biopsy.

Question 9

calcium high at 10.7, alkaline phosphatase very low at 10. negative parathyroid, not anemic, celiac, copper level is normal. what could be the cause?

Accepted Answer

Watch it: You may have hypocalciuric hypercalcemia, with probably isn't worth the workup as it's not something worth treating. I trust you're not taking a thiazide or dolomite pills, or overdoing milk / antacids. Unless you also have a low albumin, this is unlikely to impact your life. Low alk-phos is never worrisome. Best wishes.

Question 10

10 days post-op abdominal hysterectomy and ovary removal. bloodwork today, alkaline phosphatase is high 139. still taking pain meds. cause for concern?

Accepted Answer

Alk Phos: The answer would depend on why your doctor checked your Alkaline Phosphatase level. Typically it is done looking for gallbladder, liver and done disorders. Check with your doctor to see why the test and was done and how it can be interpreted given your current clinical scenario.

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Doctor answers about:

What are the causes of a high value alkaline phosphatase

A member asked:

What are the causes for elevated alkaline phosphatase?

A member asked:

What condition might cause an elevated alkaline phosphatase?

A member asked:

High alkaline phosphatase but everything else normal. had a total replacement 1month ago. is this the reason or what else could be?

A member asked:

What could cause alkaline phosphatase levels to steadily increase over a period of years, now at an elevated level?

A member asked:

Does elevated alkaline phosphatase cause bone pain?

A member asked:

What causes bone pain and elevated alkaline phosphatase in women?

A member asked:

I am having low and high alkaline phosphatase result. ultrasound and x-ray report shows a healthy liver. what could be the cause?

A member asked:

Hx of rectal ca sp lar, cea 4m interval rise from <0.5 to 2.4, bilirubin 0.4, alkaline phosphatase 46, alt 46, but high ast 79. what's the cause?

A member asked:

Calcium high at 10.7, alkaline phosphatase very low at 10. negative parathyroid, not anemic, celiac, copper level is normal. what could be the cause?

A member asked:

10 days post-op abdominal hysterectomy and ovary removal. bloodwork today, alkaline phosphatase is high 139. still taking pain meds. cause for concern?

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