Question 1

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Accepted Answer

The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick.

Question 2

How come clinical signs in sickle cell anemia don't appear until the child is a year old?

Accepted Answer

Sickle cell disease results from a mutation in the beta hemoglobin gene. In infants, the beta hemoglobin gene is largely not used by the body (the gene is "off"). Instead, babies use a different gene named gamma hemoglobin. The gamma hemoglobin does not carry the sickle mutation. During the 1st year of life, the body gradually switches from using gamma to beta. Thus, symptoms can be delayed.

Question 3

Can you get sickle cell anemia as an adult, but didn't have it as a child or is it a hereditary?

Accepted Answer

Sickle cell disease  is often diagnosed in newborn period through newborn screening.

Question 4

If you have sickle cell anemia, what are the chances you'll pass it on to your children?

Accepted Answer

If your partner does not carry the gene, all your babies would be carriers. If your partner is a carrier, the risk is 50% with any pregnancy.

Question 5

Both carriers of sickle cell anemia. what can you tell them about their chances of any child of theirs exhibiting this disease?

Accepted Answer

Any conception of two sickle cell carriers could produce :sickle cell disease (1/4), carrier(2/4) normal(1/4). It is important to stress, any pregnancy could produce ss sickle cell disease no mater if the previous pregnancy did or did not. Many state newborn screening programs look for ss or s trait. If baby gets a s gene from each parent they will get sick. Carriers generally do not.

Question 6

What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?

Accepted Answer

If both parents have trait, then the child has a 25% chance of having sickle cell disease, a 50% chance of having trait, and a 25% chance of not inheriting any mutation.

Question 7

How come clinical signs in sickle cell anemia don't appear until the child is at least 12 months old?

Accepted Answer

The hemoglobin involved with sickle cell develops after birth. Children are born with a different hemoglobin type and this changes over the first 3-6 months to be sickle hemoglobin. This is what delays the syptoms of sickle cell.

Question 8

If my boyfriend has sickle cell anemia and i don't have neither the trait or disease, will our child end up having it?

Accepted Answer

The children will not have sickle disease but they will become a carrier, sickle trait.

Question 9

Can sickle cell anemia retard a child's growth? can steroids help?

Accepted Answer

Growth failure and delayed puberty are common in children with scd. Most have detectable growth retardation that affects weight more than height by the age of two years. Tratment with Hydroxyurea early and close f/u is necessary.

Question 10

What are symptoms of sickle cell anemia in school children?

Accepted Answer

Sickle cell disease is seldom subtle.  Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc.  This is a very bad disease with few subtle manifestations.

Sickle cell anemia catchy slogans for kids

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

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How come clinical signs in sickle cell anemia don't appear until the child is a year old?

Can you get sickle cell anemia as an adult, but didn't have it as a child or is it a hereditary?

If you have sickle cell anemia, what are the chances you'll pass it on to your children?

Both carriers of sickle cell anemia. what can you tell them about their chances of any child of theirs exhibiting this disease?

What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?

How come clinical signs in sickle cell anemia don't appear until the child is at least 12 months old?

If my boyfriend has sickle cell anemia and i don't have neither the trait or disease, will our child end up having it?

Can sickle cell anemia retard a child's growth? can steroids help?

What are symptoms of sickle cell anemia in school children?

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