Question 1

what is the relationship of her2 and p53 with hormone receptors in breast cancer?

Accepted Answer

Complicated: Her-2 is an oncogene usually (not always) associated with er- tumors. We know that it is in general associated with a worse prognosis, but women with her 2+ tumors may respond dramatically to Herceptin (trastuzumab) - a monoclonal antibody.  P53 is a tumor suppressor gene. The relationship between p53 and er is currently under study - it may be that p53 mutations may play a role in tamoxifen responsiveness.

Question 2

could there be a connection between breast cancer and abortion?

Accepted Answer

No: But there is a connection with number of pregnancies, ( more is protective) age of the woman, hormone therapy, alcohol, smoking, family history (genetic factors) etc. Etc. Are few among the many other risk factors. Statistically according to some 1 in 7 women will come down with the condition, thus early dg is imperative!

Question 3

is there a connection between women who have late pregnancies and breast cancer?

Accepted Answer

Yes: Analysis of statistics shows women who have earlier age at first menstrual cycle, first childbirth at a later age & those who do not breast feed can have higher risks of breast cancer. But does not mean that all of those will get breast cancer.

Question 4

is there a connection between breast cancer and apl leukemia? there are two cases of breast two cases of leukemia in my cousins family.

Accepted Answer

No: There is no association or reported instances of leukemia associated with breast cancer.  The closest that one can find is a rare association between lymphoma, probably arising in a intramammary lymph node and carcinoma in the same breast .  There is the possibity that the cause is the MMTV virus that has entered the Wnt-1 gene to overproduce B-catenin.

Question 5

is there a connection between inverted nipples and breast cancer?

Accepted Answer

Sometimes: Having inverted nipples chronically or over a long time does not have a connection with breast cancer. But the new onset of nipple inversion can be associated with a breast mass and breast cancer. New breast changes that you see should be evaluated by your doctor.

Question 6

what is the current theory about the connection between breast cancer and abortion?

Accepted Answer

No increased risk: The american college of OB gyn made this statement "early studies of the relationship between prior induced abortion and breast cancer risk were methodologically flawed. More rigorous recent studies demonstrate no causal relationship between induced abortion and a subsequent increase in breast cancer risk.".

Question 7

my younger sister died of breast cancer at age 33.  my mother recently died of cancer unknown primary.  is there a connection?  what can i do to protect myself? i am convinced that i will die of cance

Accepted Answer

Genetic Counseling: Start with genetic counseling and consider genetic testing if recommended.

Question 8

hello, is there are connection between breast cancer and high rbc folate (folic acid) level. my rbc folate (folic acid) level is 2242 mmol/l. i've had cancer twice within 4yrs.

Accepted Answer

Indirectly: high folate (folic acid) levels have been shown to be assocaited with methylation of tumor suppressor genes which make the inciting factor more capable of inducing a malignant transformation.  While the folate (folic acid) levels do not induce cancer they may allow an MMTV virus which could be associated with breast cancer to allow the transformation process to happen at a shorter period of time.

Question 9

there's a white spot on my legs and arms and its itchy . im a breast cancer patient taking up herceptin (trastuzumab) is there a connection ?what ointment could you

Accepted Answer

Should be seen: I suspect a superficial fungus but there's several other possibilities; if it has not responded to a topical antifungal such as tolnaftate after a few days, a physician's office visit is in order.

Question 10

is there any links between cervical cancer and breast cancer?

Accepted Answer

Ovarian cancer: And  breast cancer are related in that certain genetic defects make a person more susceptible to develop both.  No such correlation with cervical cancer.  Causes of malignancy are multifactorial, and we are just beginning to understand them.

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Relationship between duodenal cancer and breast cancer

A member asked:

What is the relationship of her2 and p53 with hormone receptors in breast cancer?

A member asked:

Could there be a connection between breast cancer and abortion?

A member asked:

Is there a connection between women who have late pregnancies and breast cancer?

A member asked:

Is there a connection between breast cancer and apl leukemia? there are two cases of breast two cases of leukemia in my cousins family.

A member asked:

Is there a connection between inverted nipples and breast cancer?

A member asked:

What is the current theory about the connection between breast cancer and abortion?

A member asked:

My younger sister died of breast cancer at age 33. my mother recently died of cancer unknown primary. is there a connection? what can i do to protect myself? i am convinced that i will die of cance

A member asked:

Hello, is there are connection between breast cancer and high rbc folate (folic acid) level. my rbc folate (folic acid) level is 2242 mmol/l. i've had cancer twice within 4yrs.

A member asked:

There's a white spot on my legs and arms and its itchy . im a breast cancer patient taking up herceptin (trastuzumab) is there a connection ?what ointment could you

A member asked:

Is there any links between cervical cancer and breast cancer?

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