Question 1

how can a radiologist tell whether lesions on the brain are from a demyelinating process (ex. ms) or brain metastasis from an unknown cancer??

Accepted Answer

Usually evident: Radiologists are trained to interpret various lesion patterns on films, and each disorder has characteristic features.  The classical MS lesion is periventricular, and perpendicular to the ventricle (Dawson's fingers).  The typical metastasis is isolated toward the grey-white junction &amp; likely surrounded by edema.  A tough call is tumefactive MS which can be confusing.

Question 2

what's a metastasis?

Accepted Answer

Metastasis = spread: Metastasis refers to the spread of cancer to area(s) of the body not contiguous with the original cancer, often other organs such as lung, liver or bone. This means the cancer has "spread".

Question 3

how can metastasis occur?

Accepted Answer

3 factors: The tumor must produce matrixmetalloproteinase (MMP) to allow entry into the blood stream. The MMP must breakdown -cadherin to small e cadherin for progression of tumor growth and new cells invading circulation must express a surface antigen that determins site of implantation.  Ovary spread to omentum where TGF beta present,  Colon to liver because matrix contains liver ferritin.

Question 4

what is the cascade of metastasis?

Accepted Answer

Describes the biolog: Metastases is a complex process with many steps(often called cascade) that cancer cells released from a primary cancer go thru to reach and establish as distant metastases.

Question 5

what does a drop metastasis mean ?

Accepted Answer

unusual term!: It is something, used when there is a tumor in a lower organ(like in ovary) when the starting organ is located high up in the abdomen, like it can be from stomach cancer. But it is not always an exact term in its causation.

Question 6

how many types of metastasis present?

Accepted Answer

Cancer spread: Metastasis means that the cancer spread to a different location via the blood, lymphatics, or other means. Cancer can go almost anywhere in the body depending on where it started.

Question 7

are metastasis and metastases synonymous?

Accepted Answer

Singular/pleurals: Used for one metastasis or more metastases!

Question 8

what is the definition or description of: metastasis?

Accepted Answer

Metastasis: Is the spread of a disease from one organ or part to another non-adjacent / distant  organ or part. Different ways of metastasis-can happen via blood, or lymphatic organ.

Question 9

are multi spinocelluar ephiteliomas sign of metastasis? thanks

Accepted Answer

Metastases from what: Assuming you mean SQUAMOUS CELL CARCINOMA, your question makes no sense without details. Does "multi" mean 3? More? How many? All at once or over some years? Are they in areas exposed to sun or radiation? Are they in anal or genital area? Do you have a transplant? On meds? What is your understanding of "METASTASIS"? Evaluation and treatment should be done by a skin specialist.

Question 10

what's metastasis, and how does it happen? by blood?

Accepted Answer

Spread: This can happen in many ways. It can occur through the blood stream, lymph system or by moving through the local tissues.

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Doctor answers about:

Process of metastasis

A member asked:

How can a radiologist tell whether lesions on the brain are from a demyelinating process (ex. ms) or brain metastasis from an unknown cancer??

A member asked:

What's a metastasis?

A member asked:

How can metastasis occur?

A member asked:

What is the cascade of metastasis?

A member asked:

What does a drop metastasis mean ?

A member asked:

How many types of metastasis present?

A member asked:

Are metastasis and metastases synonymous?

A member asked:

What is the definition or description of: metastasis?

A member asked:

Are multi spinocelluar ephiteliomas sign of metastasis? thanks

A member asked:

What's metastasis, and how does it happen? by blood?

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