Question 1

what are symptoms of osteonecrosis of the jaw?

Accepted Answer

Exposed bone: Osteonecrosis of the jaw can be from a variety of medical issues.  Meaning, dead bone, osteonecrosis can be a result of radiation, certain medications or chronic infection.  Symptoms can range from a constant draining of an abscess through the skin to exposed painless bone in the mouth.  See your oral and maxillofacial surgeon if you are concerned.  This is a very serious condition.

Question 2

i was wondering what are symptoms of osteonecrosis of the jaw?

Accepted Answer

Osteonecrosis of jaw: Onj- the exposure of mandibular or maxillary bone through lesions in the gingiva that does not heal; pain and inflammation of the surrounding soft tissues, and possibly secondary infection or drainage.

Question 3

how painful is osteonecrosis of the jaw?

Accepted Answer

Osteonecrosis: This most often is painful but there are times where there is not much pain. You cannot use this as diagnostic symptom. You need to have your dentist evaluate things to make sure what is going on.

Question 4

what is osteonecrosis of the jaw?

Accepted Answer

A drug side-effect: The drugs for osteoporosis and metastatic bone cancer called bisphosphonates (includes fosamax, actonel, boniva, reclast, (zoledronic acid) zometa, aredia) are associated with a side-effect where part of the bone of the jaw dies, the gum sloughs off, and bone shows where the gum was lost.  It is treatable but not always curable.  It has also been found with bevicizumab, an anti-cancer drug, and after jaw radiation.

Question 5

why could you have to have your jaw removed with osteonecrosis of the jaw?

Accepted Answer

Could save...: It could save you from loosing more of your jaw...

Question 6

i was wondering what is the risk of fosamax (alendronate) to osteonecrosis of the jaw?

Accepted Answer

Osteonecrosis: Fosamax (alendronate) ; other drugs in the same drug class increase the risk of osteonecrosis following extractions and other dental surgery. However, it tends to occur mostly with IV and long term use. See http://www.Webmd.Com/osteoporosis/news/20090101/fosamax-higher-risk-of-jawbone-death.

Question 7

what are the risks of fosamax (alendronate) to osteonecrosis of the jaw?

Accepted Answer

Biphosphonates: From: http://www.merck.com

ONJ, which can occur spontaneously, is generally associated with tooth extraction and/or local infection with delayed healing, and has been reported in patients taking bisphosphonates, including FOSAMAX (alendronate). Clinical judgment of the treating physician and/or oral surgeon should guide the management plan of each patient based on individual benefit/risk assessment.

Question 8

how much of a risk of osteonecrosis of the jaw is associated with fosamax (alendronate)?

Accepted Answer

See details: This is a very rarely phenomenon and has been associated most likely after dental implants or extractions, not after routine dental care. The incidence has been estimated at 3 per 100, 000 users of fosamax (alendronate).

Question 9

can you tell me more about problem with fosamax (alendronate) and osteonecrosis of the jaw?

Accepted Answer

Low risk: There is a definite but low risk of developing osteonecrosis (dead bone) in patients who have taken fosamax (alendronate). The risk is higher for other bone building medications taken intravenously. Patients taking Fosamax (alendronate) should discuss any dental procedures with the dentist to see if special precautions must be taken. Sometimes, a 3 month holiday from Fosamax (alendronate) is helpful to minimise the risk of osteonecrosis.

Question 10

can aromatose inhibitors cause osteonecrosis of the jaw? i know bisphosphanates can, but what about other meds?

Accepted Answer

They do not!: Since they lower Estradiol levels, they can make osteoporosis more likely, but the do not cause osteonecrosis of the jaw! obviously used for estrogen receptor positive breast ca, Evista (raloxifene) would be a good trade for your tamoxifen, in the sense that it would prevent osteoporosis as well as breast ca!

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Doctor answers about:

Jaw osteonecrosis symptoms

A member asked:

What are symptoms of osteonecrosis of the jaw?

A member asked:

I was wondering what are symptoms of osteonecrosis of the jaw?

A member asked:

How painful is osteonecrosis of the jaw?

A member asked:

What is osteonecrosis of the jaw?

A member asked:

Why could you have to have your jaw removed with osteonecrosis of the jaw?

A member asked:

I was wondering what is the risk of fosamax (alendronate) to osteonecrosis of the jaw?

A member asked:

What are the risks of fosamax (alendronate) to osteonecrosis of the jaw?

A member asked:

How much of a risk of osteonecrosis of the jaw is associated with fosamax (alendronate)?

A member asked:

Can you tell me more about problem with fosamax (alendronate) and osteonecrosis of the jaw?

A member asked:

Can aromatose inhibitors cause osteonecrosis of the jaw? i know bisphosphanates can, but what about other meds?

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