Question 1

is it even possible to have polycythemia vera with a negative jak2 mutation?   current lab results are on previous question. biopsy performed 04

Accepted Answer

Yes: There is another mutation called, exon 12 in about 1-5% of the pv. And rarely there other. Mutations that we do not. Know

Question 2

do a lot of people get polycythemia vera?

Accepted Answer

Not common: According to one study, about 65,000 people in the US have this condition, or about 22 out of every 100,000 people.  http://www.ncbi.nlm.nih.gov/pubmed/18181200.

Question 3

im a teen. how will having polycythemia vera mess up my health later in life?

Accepted Answer

No: Generally speaking, pvera dose not imapct a persons long term survival, ie when comparing a group of patients with pv to a group without, survial rates are the same.  However, pv and other myeloproliferative disorders are uncommon in your age group and i would be skeptical of the diagnosis.

Question 4

are there any two types of polycythemia vera?
please give me a clear explanation.

Accepted Answer

No: There are two types of polycythemia. Primary Polycythemia (Polycythemia Vera) is an abnormal proliferation of blood cells, leading to too many red blood cells. It is not caused by any other factor. Secondary Polycythemia is a high red cell count caused by another factor, such as being at altitude, sleep apnea, administration of erythropoietin, or several others. Hope this helps!

Question 5

would polycythemia vera cause a low rdw?

Accepted Answer

Not that I know of.: The big changes of this are elevated rbc count, hemoglobin, hematocrit, and decreased ESR (erythrocyte sedimentation rate).  The elevations come without decrease in volume, and can be up to 70-80% for hematocrit, and 8-9 million rbc count.  Changes in RDW may be from so many rbc's in the system, but even if they do occur, do not apparently have effect on prognosis or relevance to the cause of this.

Question 6

is polycythemia vera a type of cancer?

Accepted Answer

As below: Polycythemia vera is a type of cancer of the bone marrow where your blood cells (white/red cells, platelets are produced). It is one of the chronic myeloproliferative neoplasms where there is a clonal proliferation of myeloid cells. In PV there is an elevated red blood cell mass (RCM). This can cause high Hct &gt;= 32 in W. Also Platelet count &amp; White blood cell count could be elevated too.

Question 7

what is polycythemia vera?

Accepted Answer

High red blood cell : This means the red blood cell count is high (seen in blood test) without any cause--not from smoking, dehydration or living in high altitude.

Question 8

is polycythemia vera hereditary?

Accepted Answer

Sometimes.: Most patients with polycythemia vera develop the condition in adulthood, most commonly from an acquired mutation in the jak2 gene, and are not born with it.  However, there are families who pass on the tendency to have a high red blood cell count through a variety of genetic mutations.  It is usually well known in the family when that is the case.

Question 9

how's diagnosed polycythemia vera?

Accepted Answer

Your Doctor is guide: P. Vera is a rare condition. It is not difficult to diagnose provided you have consulted a specialist...A hematologist is the right specialist to help you with this issue. It typically manifests with high hemoglobin( &gt;17 grams) and often has high white blood cell count as well as high platelets associated with high hemoglobin levels.

Question 10

how can you treat polycythemia vera?

Accepted Answer

Depends: It can be a primary problem treated with removal of blood (thereby reducing iron) or it may be due to extrinsic factors (high altitude, smoking, carbon monoxide poisoning, etc) in which case avoiding the factor may be the treatment.

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Jak2 negative polycythemia vera

A member asked:

Is it even possible to have polycythemia vera with a negative jak2 mutation? current lab results are on previous question. biopsy performed 04

A member asked:

Do a lot of people get polycythemia vera?

A member asked:

Im a teen. how will having polycythemia vera mess up my health later in life?

A member asked:

Are there any two types of polycythemia vera? please give me a clear explanation.

A member asked:

Would polycythemia vera cause a low rdw?

A member asked:

Is polycythemia vera a type of cancer?

A member asked:

What is polycythemia vera?

A member asked:

Is polycythemia vera hereditary?

A member asked:

How's diagnosed polycythemia vera?

A member asked:

How can you treat polycythemia vera?

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