Question 1

what are the different layers of adrenal cortex?

Accepted Answer

3 layers: Zona glomerulosa, zona fasciculata and zona reticularis.

Question 2

how does cortisone damage adrenal cortex?

Accepted Answer

Supression: Adrenal gland produces cortisol. External sources of cortisol(cortisone) will suppress the normal adrenal function.

Question 3

how can taking cortisone damage the adrenal cortex?

Accepted Answer

Suppresses it: Taking the hormone that is normally produced by the adrenal cortex means that it no longer produces it (negative feedback). If you suddenly stop taking the medication, your body needs several days to weeks to begin to make hormone again. So, if you are taking cortisol you need to taper the dose to make sure you give your glands the chance to being producing again.

Question 4

does cortisone in high doses damage the adrenal cortex?

Accepted Answer

Prolonged use, yes: Using steroid for a brief period of time of less than a few weeks probably won't have long term effect, but prolonged use will suppress it--it loses the ability to produce the steroid. Thus folks who need to use steroid for an extended of time often need to remain on it. The length of time varies, but using more than 3 wks typically would need a slow wean. Consult doc. Good luck.

Question 5

how could taking cortisone chronically damage the adrenal cortex?

Accepted Answer

Causing hypoadrenal: The adrenal cortex makes Hydrocortisone under the influence of acth from the pituitary. Too much cortisone will suppress the pituitary so it will not stimulate the adrenal to produce its own steroid. After taking cortisone in tapering amounts the adrenal will eventually wake up.

Question 6

what hormone is produced by the adrenal cortex?

Accepted Answer

Rather 3 not 1: In a nutshell: 1- Cortisol, which is cortisone important for several metabolic functions,its release is regulated by the pituitary gland in the brain, 2- Aldosterone, plays a role in controlling blood pressure and balancing salts in circulation,   and 3- acts a secondary site for producing Androgens, as testosterone and others, which have several effects on muscle mass and cell growth,

Question 7

what occurs to the adrenal cortex if you take to much steroids?

Accepted Answer

Shrinks down: If you do not use a gland, it tends to atrophy, or shrink.  If you take steroid pills, your adrenals do not need to produce any, and the glands atrophy.  The cells, however, do not die, so they will come back, but it can take time, depending on how long you were on steroids and what dose.

Question 8

what happens to the adrenal cortex if you take too much steroids?

Accepted Answer

How much? How long?: It depends on the steroids potency (they differ), the length of time you take it, and the amount you are taken. Very modest suppression can occur within a week, because acth production by the pituitary will decrease, but reawaken in a couple of days.  However high doses for along period (1mo) will atrophy the adrenal gland and you will need to taperm commencing with an alternate day regimen.

Question 9

could you tell me what happens to the adrenal cortex if you take to much steroids?

Accepted Answer

Adrenal suppression: Taking large dose of steroids orally for a long time and suddenly stopping them may lead to adrenal crisis and death. This is manifested as shock that doesn't respond to common blood pressure-raising medications.

Question 10

if the adrenal cortex is not working properly does that means all of its hormones are affected?

Accepted Answer

Adrenal cortex: If you have addison's disease, you will lose production of cortisol, and often aldosterone (na/k balance) too.  Epinephrine is not usually affected.  Beware of the diagnosis of "adrenal fatigue".  Adrenals respond to the situation at hand.  They can fail (i.e. Addison's), but don't usually fatigue.   If you are being told this, see an endocrinologist to make sure about the diagnosis.

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Hyposecretion of the adrenal cortex

A member asked:

What are the different layers of adrenal cortex?

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How does cortisone damage adrenal cortex?

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How can taking cortisone damage the adrenal cortex?

A member asked:

Does cortisone in high doses damage the adrenal cortex?

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How could taking cortisone chronically damage the adrenal cortex?

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What hormone is produced by the adrenal cortex?

A member asked:

What occurs to the adrenal cortex if you take to much steroids?

A member asked:

What happens to the adrenal cortex if you take too much steroids?

A member asked:

Could you tell me what happens to the adrenal cortex if you take to much steroids?

A member asked:

If the adrenal cortex is not working properly does that means all of its hormones are affected?

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