Question 1

how small is the so called "small" risk of acquiring something bad from hepatitis b immune globulin (hbig) used as hbv pep (blood-derived product)?

Accepted Answer

Very very small: Modern treatment of Immune Globulin products has pretty much eliminated fear for hepatitis or hiv.   However one is always concerned over prion which is a particle not degraded by alcohol or heat and can cause a severe neurologic condition. However I have not heard of a single case of this condition induced by immune globulin. Thus there is a risk which is as remote as being struck by lightning.

Question 2

if immune globulin is given one week in advance of exposure will it prevent hepatitis a?

Accepted Answer

Depends on dose: Immunoglobulin preparations are not checked if they have protective level antibodies anti-hepatitis a. Assuming that most blood donors have enough antibodies anti-hepatitis a, the immunoglobulin preparations should also have enough to neutralize a potential infection. However, this is especulation and it is possible that there could be enough viruses to overcome the neutralzing antibodies received.

Question 3

can anyone describe their experience with immune globulin shots given to prevent hepatitis a?

Accepted Answer

It works: Both Immune Globulin and the hep a vaccine are approved for post exposure prophylaxis, and they work.  The choice between the two depends upon availability and a variety of patient factors.

Question 4

can hepatitis b immunoglobulin cause false positive hiv test?

Accepted Answer

: No

Question 5

can hepatitis b immunoglobulin injection cause false positive hiv test 4 th generation ?

Accepted Answer

: No. IVIG will not result a positive test for HIV antigen.

Question 6

do asian plasma donation centers check for hepatitis b immunoglobulin?

Accepted Answer

All donors screened : Regardless of who they serve.

Question 7

if a person gets vaccine/immunoglobulin for hepatitis b without first being tested for if they had it in the past, can any future tests show whether they had hep b in the past? can they find out if they had it in the past even if it didn't become chronic?

Accepted Answer

Heb B antibodies: Yes, antibody tests can help distinguish immunity induced by vaccine from immunity due to past  infection with hep B virus.

Question 8

when is the latest, post exposure, that the hepatitis b vaccine and immunoglobulin can be given to prevent infection? is 13-18 days too late?

Accepted Answer

Worth a try: if  you have never had hep B vaccine and  susceptible . this  is still a  option  if exposed, sooner  rather than later,  You should have blood  test to check you hep B status before the two shots

Question 9

when is the latest, after exposure, that the hepatitis b vaccine and immunoglobulin can be given to prevent infection? is 13-18 days too late? will getting the vaccine prevent you from being able to accurately test whether an infection occurred?

Accepted Answer

Hepatitis B: Since the incubation period is highly variable it is quite possible that receiving immunoglobulin 13-18 days after exposure may be beneficial in modulating infection it is unlikely that adding hepatitis B vaccine will make a difference. On the other hand, it will not hurt you and taking it may or may not provide further antibody stimulation.

Question 10

are there any serious risks or possible side effects from getting hepatitis b immunoglobulin? can anything bad be transmitted through the blood from it?

Accepted Answer

HBIG: Most serious side effect with the injection of any medicine or biologic product would be anaphylaxis.  Rare but possible.  Since HBIG is derived from donor serum there could be potential for transmission of infectious disease, but such products are rigorously screened for all reasonable pathogens.  Risk of Hep B is far far far greater than either of these.

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Doctor answers about:

Hepatitis b immune globulin medication

A member asked:

How small is the so called "small" risk of acquiring something bad from hepatitis b immune globulin (hbig) used as hbv pep (blood-derived product)?

A member asked:

If immune globulin is given one week in advance of exposure will it prevent hepatitis a?

A member asked:

Can anyone describe their experience with immune globulin shots given to prevent hepatitis a?

A member asked:

Can hepatitis b immunoglobulin cause false positive hiv test?

A member asked:

Can hepatitis b immunoglobulin injection cause false positive hiv test 4 th generation ?

A member asked:

Do asian plasma donation centers check for hepatitis b immunoglobulin?

A member asked:

If a person gets vaccine/immunoglobulin for hepatitis b without first being tested for if they had it in the past, can any future tests show whether they had hep b in the past? can they find out if they had it in the past even if it didn't become chronic?

A member asked:

When is the latest, post exposure, that the hepatitis b vaccine and immunoglobulin can be given to prevent infection? is 13-18 days too late?

A member asked:

When is the latest, after exposure, that the hepatitis b vaccine and immunoglobulin can be given to prevent infection? is 13-18 days too late? will getting the vaccine prevent you from being able to accurately test whether an infection occurred?

A member asked:

Are there any serious risks or possible side effects from getting hepatitis b immunoglobulin? can anything bad be transmitted through the blood from it?

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