Question 1

what is the cause of high inr levels?

Accepted Answer

INR: Inr is a measure of clotting involving factors which we block with the drug warfarin. When the inr is high the factors are being blocked and clotting is inhibited. Usually we aim for an inr of 2 to 3 times standard. Sometimes we aim higher. If not on warfarin then the liver may be damaged causing the factors to be low.

Question 2

can a hepatic dysfunction cause an elevated inr?

Accepted Answer

Yes.: Good liver function is important in the production of blood clotting factors.

Question 3

my inr level has increased constantly from therapeutic level (2-3) to recently 3.7, despite reduced warfarin dosis. what is the caused? thank you

Accepted Answer

Warfarin: New medication, diet, different generic rx and then we don't know, i often prescribe brand name Coumadin (warfarin) as there is less variation than generic rx and little room for error.

Question 4

my inr level increased, but i haven't changed my diet. it was supposed to remain 2.0-3.0. today, it was 3.2. my leg began to hurt is this the cause?

Accepted Answer

Not the cause.: Don't think the pain in your keg caused your inr to go up to 3.2. The inr typically fluctuates when you take warfarin (coumadin). 3.2 isn't bad, with small adjustments it should back to within range.

Question 5

i have been on warfarin since 2006. recently i've had inr results above 8.0 more than once. i've not changed my diet or dosage . i've always been therapeutic on current dosage until recently. what can the causes be for such elevated results ?

Accepted Answer

: There are many factors that can affect the Warfarin level. It could be that your body is simply metabolizing the medicine differently and so your level went up. The dose will need to be adjusted once your INR is where it should be. Follow up with your doctor for instructions and for dose adjustment. Good luck to you!

Question 6

what causes your inr level to go from 2.3 to 1.3 and i am in coumadin (warfarin)?

Accepted Answer

Multiple factors: Coumadin (warfarin) interacts with a number of gods and medications. Please check the following link for detailed information. http://m.circ.ahajournals.org/content/119/8/e220.full.

Question 7

what does it mean if my chromogranin test level was below the normal range? does that indicate anything? i know an elevated level is carcinoid but what about low? cga= 1.1 aptt=29 inr= 1.0

Accepted Answer

CgA normal: CgA is a screening test for certain types of cancer (mostly those involving the endocrine (hormone) system. Any value below 76 ng/ml is simply "normal."   Your APTT of 29 and INR of 1.0, which are tests of your blood clotting system, are also normal.  If you have persistent or debilitating symptoms of any kind, you need to continue to follow up with your doctor.  Best wishes.

Question 8

do low inr levels cause portal vein thrombosis pain to return in upper abdomen?

Accepted Answer

No but,,: A low INR is not a direct cause if pain.  It stands for International  Normalized Ratio and is the ratio of the patients prothrombin time to a normal prothrombin time value raised to the power of the ISI (international Sensitivity Index) or a ratio of tissue factor to a reference tissue factor.  However if it's low it can mean that the blood is clotting more and can lead to thrombosis in patients.

Question 9

how to get my pt/inr level down fast. im scheduled for surgery and was told my pt/ inr level was high. i dont understand why because im healthy and has never taken any blood thinners. i wonder if phentermine cause it to be high. weight loss pills?

Accepted Answer

: You should review the possible reasons for your elevated PT/INR.  Medications or liver issues can be potential causes.  But further workup is warranted.

Question 10

what's a high inr level?

Accepted Answer

Anything above 1.5: The INR is a measure of how "thin" the blood is, typically due to the use of prescription blood thinners such as Coumadin (warfarin).   A normal INR is 1.0.  Anything above that is abnormal.  For people on coumadin, the typical goal INR is 2.5 to 4.0 depending on the particular condition it is being used for.

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Doctor answers about:

Causes of elevated inr levels

A member asked:

What is the cause of high inr levels?

A member asked:

Can a hepatic dysfunction cause an elevated inr?

A member asked:

My inr level has increased constantly from therapeutic level (2-3) to recently 3.7, despite reduced warfarin dosis. what is the caused? thank you

A member asked:

My inr level increased, but i haven't changed my diet. it was supposed to remain 2.0-3.0. today, it was 3.2. my leg began to hurt is this the cause?

A member asked:

I have been on warfarin since 2006. recently i've had inr results above 8.0 more than once. i've not changed my diet or dosage . i've always been therapeutic on current dosage until recently. what can the causes be for such elevated results ?

A member asked:

What causes your inr level to go from 2.3 to 1.3 and i am in coumadin (warfarin)?

A member asked:

What does it mean if my chromogranin test level was below the normal range? does that indicate anything? i know an elevated level is carcinoid but what about low? cga= 1.1 aptt=29 inr= 1.0

A member asked:

Do low inr levels cause portal vein thrombosis pain to return in upper abdomen?

A member asked:

How to get my pt/inr level down fast. im scheduled for surgery and was told my pt/ inr level was high. i dont understand why because im healthy and has never taken any blood thinners. i wonder if phentermine cause it to be high. weight loss pills?

A member asked:

What's a high inr level?

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