Question 1

what is the definition or description of: propofol overdose?

Accepted Answer

Propofol: Propofol is an injectable anesthetic medicine used to initiate anesthesia for surgery or other purposes such as intubation, deep sedation etc. Overdose may lead to cessation of respiration and cardio-vascular collapse and death. Michael jackson had such an event killing him.

Question 2

what is the treatment for propofol overdose?

Accepted Answer

Supportive treatment: There is no specific antidote for too much propofol. But it is a short-acting medication. If the blood pressure is too low, the anesthesiologist will give fluids and meds to support bp. If breathing slows or stops, we would ventilate by mask and/or insert a breathing tube to support breathing. As long as the problems are recognized promptly, they are easily managed by a trained professional.

Question 3

what happens if the doctors  overdoses you on propofol?

Accepted Answer

Stop breathing: It is a sedative than suppresses breathing when too much is given.

Question 4

what happens when you overdose on propofol that actually kills you?

Accepted Answer

Several effects: There is no such thing as an absolute Propofol overdose. This is a very useful med for sedation and anesthesia. But, it will lower blood pressure, and in high doses stop breathing. It will cause a patient to relax, so that even if he/she is trying to breathe, the tongue can fall back and obstruct breathing. For all these reasons, an anesthesiologist must always supervise Propofol administration.

Question 5

does propofol cause less side effects in the elderly?

Accepted Answer

No: The pharmacology of all drugs changes with aging (lowered lean body mass & body water and higher body fat). A drug given rapidly to induce sleep will have a higher blood concentration and peak effect in the elderly: reduced BP & cardiac output (heart pumping activity) & slowed cardiac conduction. Broadly speaking, the elderly are 20% more sensitive to propofol.

Question 6

can propofol exposure cause changes in your menstrual cycles?

Accepted Answer

Menstrual changes: Propofol does not directly affect your menstrual cycles but the stress of surgery many times affects your menstrual cycle for that month.

Question 7

how common is it for propofol to cause complications during surgery?

Accepted Answer

Very uncommon: When used properly by a trained anesthesiologist the risk of complications from Propofol are very rare.  True problems only arise when it is used off market for things it is not meant for (such as a sleep aid) and/or it is administered by someone with out the proper training.

Question 8

will hemoperfusion work to remove propofol from the blood during an overdose? (hypothetically)

Accepted Answer

Yes: Charcol hemoperfusion can remove excessive propofol from the blood stream. Propofol usually has a fast clearance from the body, but long term adminstration can cause dangerous overdose symptions.

Question 9

does propofol infusion cause green urine discoloration?

Accepted Answer

: Yes, it does after a prolonged infusion.

Question 10

can propofol for colonoscopy and gastroscopy cause or worsen my taccycardia?

Accepted Answer

Propofol: Propofol is unlikely to cause or worsen tachycardia.

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Cause of propofol overdose

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What is the definition or description of: propofol overdose?

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What is the treatment for propofol overdose?

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What happens if the doctors overdoses you on propofol?

A member asked:

What happens when you overdose on propofol that actually kills you?

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Does propofol cause less side effects in the elderly?

A member asked:

Can propofol exposure cause changes in your menstrual cycles?

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How common is it for propofol to cause complications during surgery?

A member asked:

Will hemoperfusion work to remove propofol from the blood during an overdose? (hypothetically)

A member asked:

Does propofol infusion cause green urine discoloration?

A member asked:

Can propofol for colonoscopy and gastroscopy cause or worsen my taccycardia?

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