Question 1

what is alemtuzumab for? does it treat ms?

Accepted Answer

Yes.: Alemtuzumab is a monoclonal antibody directed against a marker on some lymphocytes. It has proven activity against some stages of chronic lymphocytic leukemia (and related diseases) and also on some stages of multiple sclerosis.  Alemtuzumab is the generic name. The formulation for MS has the trade name Lemtrada; the one for CLL has the trade name Campath (alemtuzumab).

Question 2

what is the molecular structure of alemtuzumab? how does it work?

Accepted Answer

Monoclonal antibody: Campath (alemtuzumab) -1H

it is a monoclonal antibody ( immunoglobulin structure)
a large protein that binds to CD 52 , a surface receptor on mature lymphocytes.

The CD 52 bearing lymphocytes will be targeted for destruction
 
This makes it a drug useful to treat CLL ,(chronic lymphocytic leukemia )
Was withdraw from the markets in 2012 to prepare for a launch of a more expensive drug to treat MS

Question 3

do you know if alemtuzumab could be used to cure multiple sclerosis?

Accepted Answer

Not a cure: But clearly one of the most potent meds ever developed for MS.  Yet could be risky, even life threatening.  However, in my research group, most of pts have been disease free for yrs, and take no current meds.  Although not a cure, certainly a valuable therapeutic intervention.

Question 4

what are side effects of campath, (alemtuzumab) and what premedication is appropriate?

Accepted Answer

Campath (alemtuzumab): Is antibody used by injection to treat chronic lymphocytic leukemia. Causes pneumonia, rash, GI upset, low blood counts.

Question 5

hello.what is the mechanism of  alemtuzumab?!

Accepted Answer

Antibody: Alemtuzumab is a humanized monoclonal antibody that is directed against a specific b- lymphocyte ( a type of white blood cells) receptor called cd-52 and used in the treatment of chronic lymphocytic leukemia . All patients receiving this drug should get prophylactic antivirals and antibiotics.

Question 6

what could cause allergies all year long?

Accepted Answer

All year long.: Most commonly dust mites and molds and pets. In rare cases, what you work around.

Question 7

what are the main causes of allergies during the winter?

Accepted Answer

Indoor allergens: There is little that pollinates in the winter. If you are in the south you may experience mountain cedar pollinating then, but in the north there isn't really anything. So allergies in the winter tend to be caused by indoor allergens (pets, etc), or are not allergies but upper respiratory infections, or irritant responses to pollution, response to cold/dry air, etc.

Question 8

i am having allergy symptoms in my house. what may cause these outbreaks?

Accepted Answer

Indoor allergies: Common indoor allergens include dust mite and animal dander.  Other less common indoor allergens are mold, cockroach, other pets (birds, rodents), and feathers (pillows, comforters).   During tree, grass or weed pollen season, pollen may blow through screens or open doors or windows, making it seem like indoor allergens.  An allergist can perform skin tests for these and have an answer in 20 min.

Question 9

what can cause crab allergies?

Accepted Answer

Depends: Crab allergy is a shellfish allergy and can develop at any time during adulthood.  Why some adults can consume crabs their entire life without any problems and others can go on to develop symptoms is unknown.  Shellfish allergy is a common adult allergen and symptoms can vary from one accidental exposure to the next so avoidance once symptoms develop is the best way to manage.

Question 10

why do allergies cause dizziness?

Accepted Answer

Yes they can: Allergies can interfere with normal nasal and ear function which then causes a problem with a structure known as semicircular canals.  These are part of the ear and help tell your brain where your head is located.

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Doctor answers about:

Cause of campath allergy

A member asked:

What is alemtuzumab for? does it treat ms?

A member asked:

What is the molecular structure of alemtuzumab? how does it work?

A member asked:

Do you know if alemtuzumab could be used to cure multiple sclerosis?

A member asked:

What are side effects of campath, (alemtuzumab) and what premedication is appropriate?

A member asked:

Hello.what is the mechanism of alemtuzumab?!

A member asked:

What could cause allergies all year long?

A member asked:

What are the main causes of allergies during the winter?

A member asked:

I am having allergy symptoms in my house. what may cause these outbreaks?

A member asked:

What can cause crab allergies?

A member asked:

Why do allergies cause dizziness?

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