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Can you have partial sickle cell disease

A 52-year-old member asked:
Dr. Shabbir Hossain
16 years experience Internal Medicine
Sickle cell trait: If you only have 1 of the two genes for sickle cell disease, you have sickle cell trait. This is a benign finding with no real symptoms. It's main sig ... Read More
Dr. Scott Diede
A Verified Doctor answered
A US doctor answered Learn more
Yes.: A person with sickle cell disease normally has two copies of the sickle cell mutation in each of their beta-hemoglobin genes (hb ss). Those with sickl ... Read More
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A 33-year-old member asked:
Dr. Michael Dugan
Specializes in Hematology
There are: Huge ranges of disease severity and associated symptoms. Careful choices and attention to medical recommendations will improve the prognosis.
Dr. Noah Federman
19 years experience Pediatric Hematology and Oncology
Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems wha ... Read More
A 44-year-old member asked:
Dr. Martin Raff
56 years experience Infectious Disease
Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound ane ... Read More
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A 38-year-old member asked:
Dr. James Ferguson
46 years experience Pediatrics
Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it ... Read More
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A 50-year-old member asked:
Dr. James Ferguson
46 years experience Pediatrics
Each carries S Trait: Recessive disorders are so named because they are not expressed unless two genes of the same type are carried in the chromasomes. Dominedt genes can s ... Read More
A 24-year-old member asked:
Dr. James Ferguson
46 years experience Pediatrics
Depends on genes: Two carrier parents have a 1/4 risk with each pregnancy of having a baby with a full blown sickle cell disorder. They have a 1/2 risk with each pregna ... Read More
A 42-year-old female asked:
Dr. Ed Friedlander
44 years experience Pathology
Unlikely: You may be a sickle carrier. Even the milder sickle variants -- sickle-thal, sickle-c -- usually get noticed beforehand.
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A 46-year-old member asked:
Dr. James Ferguson
46 years experience Pediatrics
Simple math: Any conception of two sickle cell carriers could produce :sickle cell disease (1/4), carrier(2/4) normal(1/4). It is important to stress, any pregnanc ... Read More
A 30-year-old member asked:
Dr. Liawaty Ho
23 years experience Hematology and Oncology
Same: Sickle cell anemia is sickle cell disease.
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A 33-year-old member asked:
Dr. Jay Park
Dr. Jay Park answered
50 years experience Pediatrics
No: The children will not have sickle disease but they will become a carrier, sickle trait.
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