Question 1

had a bone marrow asp and biopsy. said abnormal female karyotype and these numbers in order. add(14)(q22)(20). it was never explained. could you help?

Accepted Answer

Need mor einformatio: You need to tell us about what made you go to see your doctor in the first instance and why was a bone marrow done? Unless you have some blood disorder, we can not interpret your chromosomal change(karyotype). You will be better off asking your doctor what it means now that he has given you this worry some report.

Question 2

wife pregnancy was terminated in 3rd month and karyotyping shows chromosomal analysis of poc is found abnormal 47, --+21. is it will solve next time ?

Accepted Answer

Clarify please: I'm not sure what you are asking, but the type of abnormality you described does not usually recur in the next pregnancy.

Question 3

3 mcs no live birth. 2 mcs turner's & trisomy14 in fetus. parents karyotyping normal. what other genetic tests shld be done. risk of abnormal child ?

Accepted Answer

No need extra tests: No need for further tests before pregnancy since the parents chromosomes are normal. For early piece of mind you can consider early non-invasive genetic screening in early pregnancy.

Question 4

3 early mcs & chromosomal abnrml in all fetuses (no birth), is karyotyping of parents the only genetic testing tht can be done? names of any other pls

Accepted Answer

It's the starting pt: Parent study comes first.A person can appear normal if they carry all the proper chromosome material but with part belonging to one chromosome swapped with another.(ie, part of a #15 is on  #21) When fertilization occurs, the fetus  may get part of the mistake and not the other &amp; be defective.Some of these have a partial chance of normal birth, some would always end up a defect.See a geneticist.

Question 5

what is karyotyping?

Accepted Answer

Chromosome study: A karyotype is a visual presentation of the chromosomes present in each cell, usually derived from blood lymphocytes.  The cells are grown in tissue culture, then arrested in the stage of separation  (mitosis), then  dropped on a glass slide from about 2 feet, which breaks them open;  a dye is added to make stain them, a photo taken, then arranged into their 23 pairs, then studied for anomalies.

Question 6

what is the definition or description of: karyotyping?

Accepted Answer

See below: Karyotyping is a test to examine chromosomes in a sample of cells, which can help identify genetic problems as the cause of a disorder or disease. This test can:
•count the number of chromosomes
•look for structural changes in chromosomes

the test can be performed on almost any tissue, including:
•amniotic fluid
•blood
•bone marrow
•placenta.

Question 7

why heparin blood used in karyotyping?

Accepted Answer

To prevent clotting: This avoids blood cells sticking together.

Question 8

what happens if we assume that the vitiligo is generic disorder then can we check if it's a dominant, recesive and carrier etc. using karyotyping.?

Accepted Answer

Autoimmune: Vitiligo is usually considered an autoimmune problem. If you want to find out whether it is genetic, you will need to get a detailed history on family members with this problem.   I am not aware of any genetic markers uncovered thus far. Nonetheless if there has been no history of such a disorder among your immediate family members within 3 generations, genetic study would be meaningless.

Question 9

what's my chance to have normal baby if me or my husband have balanced translocation&we already had a ds baby? we didn't do karyotyping yet though

Accepted Answer

Genetic counselor: You need to have a karyotype done before you can determine your risk.  It would be very important for you and your spouse to see a genetic counselor to be able to better understand your risk.

Question 10

why do we use heparin as a karyotyping anticoagulant?

Accepted Answer

It stops clotting...: ...Without damaging or killing blood cells.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

Abnormal female karyotype

A member asked:

Had a bone marrow asp and biopsy. said abnormal female karyotype and these numbers in order. add(14)(q22)(20). it was never explained. could you help?

A member asked:

Wife pregnancy was terminated in 3rd month and karyotyping shows chromosomal analysis of poc is found abnormal 47, --+21. is it will solve next time ?

A member asked:

3 mcs no live birth. 2 mcs turner's & trisomy14 in fetus. parents karyotyping normal. what other genetic tests shld be done. risk of abnormal child ?

A member asked:

3 early mcs & chromosomal abnrml in all fetuses (no birth), is karyotyping of parents the only genetic testing tht can be done? names of any other pls

A member asked:

What is karyotyping?

A member asked:

What is the definition or description of: karyotyping?

A member asked:

Why heparin blood used in karyotyping?

A member asked:

What happens if we assume that the vitiligo is generic disorder then can we check if it's a dominant, recesive and carrier etc. using karyotyping.?

A member asked:

What's my chance to have normal baby if me or my husband have balanced translocation&we already had a ds baby? we didn't do karyotyping yet though

A member asked:

Why do we use heparin as a karyotyping anticoagulant?

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?