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Doctor insights on: Is It Good To Combine Prozac With Wellbutrin For Treatment Of Depression

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Dr. Pamela Pappas
4,484 doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Use alternative: Unfortunately Prozac (while an awesome drug) can interact with quite a few medications. Usually the SSRI + Wellbutrin (bupropion) combo is a great and very commonly used therapeutic option for patients suffering with depression and anxiety. There are plenty of efficacious and safer alternatives. Hope that helps! ...Read more

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Can wellbutrin (bupropion) and prozac be used together to treat anxiety and depression?

Can wellbutrin (bupropion) and prozac be used together to treat anxiety and depression?

Sure: Could be very powerful combination because they are from different classes of medications; dose proportion of both med's is very important. ...Read more

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I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

Not effective?: Need more information to understand your primary concern - is your concern the regimen is not effective, or too much? or is your concern with the regimen itself? In general I encourage keeping an open line of communication with your provider. If your concerns remain or regimen is ineffective, a second-opinion consult may help to explore treatment options further. Be well. ...Read more

Dr. Heidi Fowler
1,014 doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


Dr. Alan Ali
757 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more