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Doctor insights on: Is It Good To Combine Prozac With Wellbutrin For Treatment Of Depression

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Is it good to combine Prozac with wellbutrin (bupropion) for treatment of depression?

Is it good to combine Prozac with wellbutrin (bupropion) for treatment of depression?

May be: Wellbutin blocks the uptake of norepinephrine & Dopamine while Prozac (fluoxetine) is a ssris so they effect different neurotransmitters & may work 4 u. ...Read more

Dr. Pamela Pappas
4,587 Doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Is wellbutrin (bupropion) and prozac a good combination in addressing depression and anxiety?

Use alternative: Unfortunately Prozac (while an awesome drug) can interact with quite a few medications. Usually the SSRI + Wellbutrin (bupropion) combo is a great and very commonly used therapeutic option for patients suffering with depression and anxiety. There are plenty of efficacious and safer alternatives. Hope that helps! ...Read more

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Can wellbutrin (bupropion) and prozac be used together to treat anxiety and depression?

Can wellbutrin (bupropion) and prozac be used together to treat anxiety and depression?

Sure: Could be very powerful combination because they are from different classes of medications; dose proportion of both med's is very important. ...Read more

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I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

I'm on 80mg of Prozac, 150 mg of seroquil, 10mg brintellex and Wellbutrin (bupropion) 100mg twice a day for depression and OCD. My np doesn't want to change any.

Not effective?: Need more information to understand your primary concern - is your concern the regimen is not effective, or too much? Or is your concern with the regimen itself? In general I encourage keeping an open line of communication with your provider. If your concerns remain or regimen is ineffective, a second-opinion consult may help to explore treatment options further. Be well. ...Read more

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Is a combination of 60mg of prozac and 150mg of wellbutrin xl effective for depression, anxiety, and obsessive compulsive disorder?

Is a combination of 60mg of prozac and 150mg of wellbutrin xl effective for depression, anxiety, and obsessive compulsive disorder?

For some people: This type of treatment has to be individualized for each person. Wellbutrin is good for depression but could make anxiety worse in some patients. Prozac is good for all three disorders in most people.. ...Read more

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Seeing cnp for 4 months for adult add. Tried strattera (made me depressed) now on Prozac and wellbutrin (bupropion). Mood better. Focus not. Can I ask to try stim?

Seeing cnp for 4 months for adult add. Tried strattera (made me depressed) now on Prozac and wellbutrin (bupropion). Mood better. Focus not. Can I ask to try stim?

Yes: Strattera (atomoxetine) affects norepinephrine mainly. I would have recomment sustained release Ritalin or extened release adderal for adult. Add as long as no history of substance abuse. It is a pity this patient would be on 3 medications when only one was indicated. ...Read more

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I am taking a low dose of xanax (alprazolam) but lately feel depressed and crying. What antidepressant is ok. Tried both wellbutrin and prozac with bad side effect?

I am taking a low dose of xanax (alprazolam) but lately feel depressed and crying. What antidepressant is ok. Tried both wellbutrin and prozac with bad side effect?

Unanswerable: Xanax, (alprazolam) like all benzodiazepines, can increase symptoms of depression, although it is somewhat less likely to do that than other benzos in most people. This is a question for a psychiatrist or other mental health prescriber to answer, based on the kind of depression, its severity, exactly what side effects you had, how long you used them for and many other factors. Get advice in person, not online. ...Read more

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Is Wellbutrin (100mg 2x/day), Fluoxetine (30mg) and Abilify (aripiprazole) (1mg, 2mg after a week) a safe combination for anxiety and depression?

Is Wellbutrin (100mg 2x/day), Fluoxetine (30mg) and Abilify (aripiprazole) (1mg, 2mg after a week) a safe combination for anxiety and depression?

Probably: Depending on yourneeds the combination seems reasonable. If the fluoxetine alone or in combination with wellbutrin doesn't remove/reduce depression, the addition of Abilify (aripiprazole) often helps. If, after a time this is not helpful... you didn't say you were in psychotherapy, but I would recommend it also. ...Read more

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Due to treatment of Dr. From GAD & SAD, I am doing well with combo (60mg Prozac+150mg Wellbutrin (bupropion) XL)daily morning, Is this combo safe use without harms?

Med tx: This combination is commonly used. Of course there is potential for side effects with all medications. Combining these two medications can help address problems with serotonin, norepinephrine & dopamine. ...Read more

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Take treatment for GAD by Prozac 40 mg, my GP wants add either Buspar (buspirone) or Wellbutrin to encounter side effects of Prozac, which the safe and ideal combo?

Buspirone: You may want to talk to your doc about a psychiatry referral since it sounds like (a)he may be in over their head. Buspirone is an anti-anxiety drug, but both Prozac and Wellbutrin (bupropion) can potentially exacerbate anxiety. There are many other potential options if Buspirone is not beneficial, but I would not abandon it before max dose of 60 mg/d. It should be taken 3-4 times dailu ...Read more

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Anxiety and depression have gotten severe and debilitating. Will soon be subscribed 40 mg for prozac (fluoxetine). Also in therapy. Do you think this will help me?

Anxiety and depression have gotten severe and debilitating. Will soon be subscribed 40 mg for prozac (fluoxetine). Also in therapy. Do you think this will help me?

On right track: Prozac (fluoxetine) is a good choice for treatment of anxiety and depression. Combination of medications and therapy has been shown to help in moderate to sever depression compared to medications alone. Hopefully you should feel better soon. ...Read more

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Hi, I take 60mg fluoxetine daily for depression. Over past year I have gained 20lb in weight. Is there an alternative treatment which may help?

Hi, I take 60mg fluoxetine daily for depression. Over past year I have gained 20lb in weight. Is there an alternative treatment which may help?

Therapy?: Have you yet tried any form of psychotherapy? Typically, the optimal combination of things to treat emotional issues such as depression is medication (which, on your best day, is supposed to take the edge off symptoms) but the real gruntwork takes place in psychotherapist's consulting room. ...Read more

Dr. Heidi Fowler
1,052 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


Dr. Alan Ali
789 Doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more