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Brca2 gene
This is a normal gene that makes a protein for basic cell functions. It was the second gene discovered that is often mutated in people at extra risk for breast cancer, and depending on the mutation these people often have increased risk of ovarian cancer as well. A person with a family history may be tested for the mutation and make decisions to protect health.
Dr. Ed Friedlander reviewed this
46 year experience in Pathology
Related questions
A 34-year old asked:
What does the brca2 gene mean as a guy?
1 doctor answer • 1 doctor weighed in
A 45-year old asked:
Any stats on how many woman have been tested for the brca1 and brca2 gene?
1 doctor answer • 3 doctors weighed in
A 27-year old female asked:
Does the brca2 gene also cause colon cancer? Or just breast and ovarian?
2 doctor answers • 8 doctors weighed in
A 52-year old female asked:
53 year old male with psa result of 5.3. All other CBC perfect, including full urinalysis. No BRCA1 or BRCA2 gene. No family history of cancer (has 5 brothers) and dad still living. What are chances of cancer? Any margin of error on these tests?
1 doctor answer • 2 doctors weighed in
A 25-year old female asked:
Can u still have endometriosis or ovarian cancer w/ a clear transvaginal ultrasound? My doc says my ovaries are normal and my tiny cyst is gone. I have tons of pelvic pain & my mom has the brca2 gene.
3 doctor answers • 8 doctors weighed in
A 50-year old asked:
Are genetic tests available to detect brca1 and brca2 mutations, and how are they performed?
2 doctor answers • 5 doctors weighed in
A 40-year old female asked:
I am brca2 positive, what now?
1 doctor answer • 2 doctors weighed in
A 42-year old female asked:
What are potential risk variants on the Brca2 results? But no pathogenic variants.
1 doctor answer • 2 doctors weighed in
A 47-year old asked:
Brca1 and brca2 stands for?
2 doctor answers • 4 doctors weighed in
A 68-year old asked:
Brca2 age 68. Should I get madtectomy?
3 doctor answers • 6 doctors weighed in
A 27-year old asked:
If a man is found to have brca1 or brca2 mutations, what should his next step be?
3 doctor answers • 7 doctors weighed in
A 33-year old female asked:
Recvd rawDNA from Ancestrydna, sent to Promethease, said I had rs397507805(A;T) Magnitude 6 BRCA2 variant pathogenic for bc. Not sure what do next?
1 doctor answer • 1 doctor weighed in
A 38-year old asked:
What do brca1 and brca2 stand for?
3 doctor answers • 9 doctors weighed in
A 35-year old asked:
Who should take the brca1/brca2 test?
2 doctor answers • 6 doctors weighed in
A 40-year old asked:
How do you perform tests for brca1 or brca2?
2 doctor answers • 3 doctors weighed in
A 24-year old female asked about a 23-year old female:
What birth control is recommended for patient with brca2?
1 doctor answer • 2 doctors weighed in
A 30-year old female asked:
31, BRCA2 pos. 3.6cm cyst on right ovary that causes pain. Could be cancerous? CA125 is normal.
1 doctor answer • 1 doctor weighed in
A female asked:
I am 55 yrs of age. 15 yrs post menopause. I do not know my biological mother, or her health history. Should I get the brca2 test?
1 doctor answer • 2 doctors weighed in
A 33-year old asked:
How are brca1 and brca2 related to the development of breast cancer?
2 doctor answers • 9 doctors weighed in
A 52-year old female asked:
Can I take Osphena if I still have my cervix but no uterus and I carry BRCA2.
1 doctor answer • 2 doctors weighed in
A 36-year old female asked:
Family history of brca2. Should i worry about a 5-6 mm raised mole on my breast that is flaky and itchy. It is tan with some black specks in it.
1 doctor answer • 1 doctor weighed in
A 44-year old female asked:
I was told that if someone was treated for breast cancer 20yrs ago with tamoxifen, that they did not carry the BRCA1 & BRCA2 mutations? Is this true?
1 doctor answer • 1 doctor weighed in
A 53-year old female asked:
BRCA2+, still have breasts (non dense) and ovaries,no uterus. Can I use local estrogen for severe vaginal dryness safely?
1 doctor answer • 1 doctor weighed in
A 43-year old female asked:
10yrold son plays elite sports. Found hard lump on outside of femur, xray shows "enchondroma" dr. Says benign. Causes? Dad=7ft. Tall mom brca2 bc@35.
1 doctor answer • 2 doctors weighed in
A member asked about a 54-year old female:
What is the life expectancy of a 54yr woman with Stage 4 Breast cancer, metastasized to bones, brain and spinal fluid? BRCA2 positive
1 doctor answer • 1 doctor weighed in
A 31-year old asked:
Do my genes make me fat?
1 doctor answer • 1 doctor weighed in
A 29-year old asked:
How do genes affect the way I age?
1 doctor answer • 1 doctor weighed in
A 50-year old asked:
Do your genes determine your personality?
1 doctor answer • 4 doctors weighed in
A 36-year old asked:
Can I control which genes will be turned on?
1 doctor answer • 1 doctor weighed in
A 44-year old asked:
How powerful are thrifty genes and what do they do?
1 doctor answer • 1 doctor weighed in
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