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Conditions
Harlequin ichthyosis

Harlequin ichthyosis

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The most severe form of congenital ichthyosis, causing severe thickening of the stratum corneum (topmost layer), which then fractures into inflexible diamond-shaped plates of skin. Associated deformities involving the eyelids, ears, nose, mouth, and genitalia may be seen. Recent advances in treatment have led to survival to adulthood for some patients.

Dr. Linda Spencer reviewed this

38 year experience in Dermatology

How long it usually lasts:

Chronic (lasts years to lifelong)

Symptoms

Dry or cracking skin
Skin hardening
Skin cracking
Thick skin

Medications

Ratings show how effective doctors think these medications are at treating Harlequin ichthyosis
Isotretinoin
3.2
6 reviews

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