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Conditions
Nervous system diseases
Neuromuscular disorders
Motor neuron disease
Primary lateral sclerosis

Primary lateral sclerosis

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Motor neuron disease or ALS presents in several variable forms, and is a disease of motor neuron degeneration in brain and spinal cord. In the primary lateral sclerosis variant (only 1-3% of all cases), the disorder affects the upper motor neuron only, and is focal on one side or the other. By definition, this form would be far less malignant.

Dr. Bennett Machanic reviewed this

47 year experience in Neurology

How long it usually lasts:

Chronic (lasts years to lifelong)

Body locations

Head

Symptoms

Muscle cramps or spasms
Dizziness
Hoarse voice
Balance problems
Difficulty swallowing
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Medications

Ratings show how effective doctors think these medications are at treating Primary lateral sclerosis
Muscle relaxants

Other treatments

Occupational therapy
Speech therapy
Dietary changes
Physical therapy

Tests

HIV test
Creatine kinase
Voltage gated calcium channel antibodies
Sod1 mutation testing
Repetitive nerve stimulation
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Related questions

A 33-year old asked:

What is primary lateral sclerosis?

1 doctor answer • 3 doctors weighed in

A 30-year old asked:

Primary lateral sclerosis only 1 side, is this normal?

1 doctor answer • 2 doctors weighed in

A 29-year old male asked:

What is the definition or description of: primary lateral sclerosis?

1 doctor answer • 1 doctor weighed in

A 33-year old asked:

Can you tell me if emg tests can be normal with primary lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 52-year old male asked:

Treatment for upper motor neuron sympathy for my diagnose of primary lateral sclerosis ?

1 doctor answer • 1 doctor weighed in

A 40-year old male asked:

I have been diagnosed with primary lateral sclerosis by my neurologist here in savannah. What's the chance of mine changing to als? Really concerned.

2 doctor answers • 2 doctors weighed in

A 31-year old asked:

How much time does it take to loose legs arms speaking if they tell ya primary lateral sclerosis?

1 doctor answer • 4 doctors weighed in

A 46-year old asked:

What exactly is amyotrophic lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 37-year old asked:

Is primary progessive multiple sclerosis always fatal?

1 doctor answer • 1 doctor weighed in

A 35-year old asked:

A friend of mine was recently diagnosed with primary progressive multiple sclerosis. Is this a fatal disease?

1 doctor answer • 1 doctor weighed in

A 33-year old asked:

Who first discovered amyotrophic lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 34-year old asked:

What are the tests for amyotrophic lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 35-year old asked:

What sort of problem is amyotrophic lateral sclerosis?

1 doctor answer • 7 doctors weighed in

A 24-year old asked:

How is amyotrophic lateral sclerosis transmitted in humans?

2 doctor answers • 5 doctors weighed in

A 41-year old asked:

Hi doctors, was just wondering what is amyotrophic lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 48-year old asked:

What is the treatment for amyotrophic lateral sclerosis?

1 doctor answer • 3 doctors weighed in

A 48-year old asked:

Could kids get amyotrophic lateral sclerosis?

1 doctor answer • 2 doctors weighed in

A 24-year old asked:

What does it mean when a guy has amyotrophic lateral sclerosis?

3 doctor answers • 10 doctors weighed in

A 44-year old asked:

What are the challenges of living with amyotrophic lateral sclerosis?

1 doctor answer • 1 doctor weighed in

A 33-year old male asked:

What is the definition or description of: Amyotrophic lateral sclerosis?

1 doctor answer • 1 doctor weighed in

A 36-year old asked:

What are the main causes of amyotrophic lateral sclerosis? What can be done to treat it?

1 doctor answer • 1 doctor weighed in

A 42-year old asked:

Just heard a close neighbor has amyotrophic lateral sclerosis. How do we explain this condition to the kids?

4 doctor answers • 13 doctors weighed in

A male asked:

I have a primary progressive multiple sclerosis and for the last three months I have had uncontrollable frustrating itchingtopical cream's prescribed ?

2 doctor answers • 2 doctors weighed in

A 40-year old male asked about a 69-year old female:

Last advances in the investigation on amyotrophic lateral sclerosis?

1 doctor answer • 3 doctors weighed in

A 41-year old asked:

Is it true that amyotrophic lateral sclerosis is a chromosomal error?

1 doctor answer • 1 doctor weighed in

A 36-year old asked:

Do you know if amyotrophic lateral sclerosis is sex linked or a chromosomal error?

2 doctor answers • 2 doctors weighed in

A 22-year old female asked:

My grandma has Amyotrophic lateral sclerosis and what medicine she should take for relieving the pain? or preventing the further complications?

2 doctor answers • 3 doctors weighed in

A 45-year old asked:

What's are future treatments for amyotrophic lateral sclerosis (als)?

1 doctor answer • 2 doctors weighed in

A 33-year old asked:

Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

1 doctor answer • 3 doctors weighed in

A 33-year old asked:

What do you suggest if my mom has amyotrophic lateral sclerosis. (lou gehrigs)?

1 doctor answer • 1 doctor weighed in

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