Unpredictable reactions to Aspirin including: 1) acute asthma in persons with nasal polyps and persistent asthma; 2) anaphylactic reactions; 3) hives and/or angioedema; 4) flare of hives in 25% of persons with chronic hives. Skin or blood tests are of no help with diagnosis. Usually not believed to be ige mediated, but instead related to lipoxygenase products such as leukotrienes.
35 year experience in Allergy and Immunology
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