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Urticaria and angioedema
Familial cold urticaria

Familial cold urticaria

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Familial cold urticaria (also known as familial cold autoinflammatory syndrome, fcas) is an autosomal dominant condition characterized by rash, conjunctivitis, fever/chills and arthralgias elicited by exposure to cold. There is a genetic predisposition nad treatment with anakinra, il-1 receptor antagonist also used to treat rheumatoid arthritis, has been shown to be effective.

Dr. Alyson Simpson reviewed this

19 year experience in Allergy and Immunology

Is a type of:

Urticaria and angioedema

How long it usually lasts:

Chronic (lasts years to lifelong)

How common it is:

Common

Related questions

A 42-year old asked:

What are the most common symptoms of familial cold urticaria?

2 doctor answers • 6 doctors weighed in

A 34-year old asked:

Are some people more prone to getting familial cold urticaria?

1 doctor answer • 3 doctors weighed in

A 34-year old asked:

Do doctors see a lot of patients with familial cold urticaria?

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What's the best treatment to get rid of familial cold urticaria?

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A 59-year old female asked:

Is there a connection between sarcoid and cold urticaria?

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A 30-year old female asked:

Why would a 25 yr old without any other health problems suddenly develop cold contact urticaria?

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A 31-year old female asked:

I have cold urticaria .....Why do I breakout when i get into a hot tub?

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A 37-year old asked:

Whats cold contact urticaria?

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A 37-year old asked:

How to tell if my cold urticaria is gone or when it will come back?

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A 35-year old asked:

I have raynaud's and cold-induced urticaria. Does this put me at any greater risk for a stroke?

2 doctor answers • 8 doctors weighed in

A 47-year old asked:

Can cold urticaria be temporary?

1 doctor answer • 4 doctors weighed in

A 41-year old asked:

What to do if I have cold urticaria. how to cure it permanently?

1 doctor answer • 1 doctor weighed in

A 18-year old male asked:

I am suffering from cold urticaria since six month.I was prescribed many medicine but they don't work at all.I want permanent cure from this disease.

1 doctor answer • 3 doctors weighed in

A 30-year old female asked:

Can eczema and cold urticaria be associated with each other?

1 doctor answer • 1 doctor weighed in

A 34-year old asked:

I seem to have cold urticaria (aka- cold rash). What can I do?

1 doctor answer • 2 doctors weighed in

A 40-year old female asked:

How likely is it for someone to have urticaria pigmentosa and cold urticaria? And should I be more worried about symptoms with my son having both?

1 doctor answer • 2 doctors weighed in

A 32-year old asked:

Could someone have cold urticaria and raynauds at the same time?

1 doctor answer • 1 doctor weighed in

A 30-year old female asked:

If healthy 25 yr old sudden developed cold urticaria how likely would it be that it's associated with an underlying autoimmune disease or other issue?

2 doctor answers • 2 doctors weighed in

A 23-year old female asked:

Hi, can i infect my partner if i have the allergy (cold Urticaria)?

1 doctor answer • 3 doctors weighed in

A 34-year old female asked:

My son has cold urticaria w/ anaphylaxis. He has started having irregular heartbeats with some (non anaphylactic) reactions. What is causing this?

1 doctor answer • 3 doctors weighed in

A 32-year old female asked:

What causes cold urticaria and solar urticaria in the same patient? Could it be an hhv6 infection/encephalitis she had at 18 months?

1 doctor answer • 1 doctor weighed in

A 25-year old female asked:

I was diagnosed with IgA nephropathy two years ago an I have always been allergic to cold weather. I think it might be cold urticaria. What shall ido?

1 doctor answer • 2 doctors weighed in

A 19-year old female asked:

One of siblings has an autoimmune issue and some blood issue, the doctors are still figuring out. But I myself have Rainauds, just developed cold urticaria, but have also been experiencing occasional muscle weakness/shakiness. Should I get tested?

1 doctor answer • 1 doctor weighed in

A 16-year old female asked:

I'm 16 years old my hands and feet are constantly cold and sweating all year round I also have cold urticaria, how can I stop the sweating?

1 doctor answer • 1 doctor weighed in

A 21-year old female asked:

I have urticaria. Cause: extreme cold air. My skin Inflames. Face. Legs. Hands. Face. How can I prevent this from happening? Goes away when warm again

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A 24-year old female asked:

Diagnosed with chronic urticaria, frequent severe nose bleeds, petechiae, flushing chest and face, cold intolerance, mild ibs, could these be relate?

1 doctor answer • 5 doctors weighed in

A member asked:

I am 25year old, i m suffering from urticaria from 10 year.. Please sir/mam suggest me what can I do? Whenever i feel cold its get on my buttock, knee albow, hand. Legs only

1 doctor answer • 2 doctors weighed in

A 30-year old asked:

Is there a simple remedy to urticaria?

1 doctor answer • 4 doctors weighed in

A member asked:

Do people with urticaria have a lot of pain?

1 doctor answer • 1 doctor weighed in

A 48-year old asked:

Is it okay to take a shower when you have urticaria?

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