9 doctors weighed in:

How have the treatments for breast cancer changed from the past 20 years?

9 doctors weighed in
Dr. Barry Rosen
Surgery
6 doctors agree

In brief: Alot!

Chemo: molecular staging leading to more precise targeted therapy; new drugs such as Herceptin (trastuzumab) and aromatase inhibitors.
Surgery: increased breast conserving rx, sentinel ln biopsy, oncoplastic surgery, nipple-sparing mastectomy. Radiation therapy: partial breast irradiation (brachytherapy, intraoperative radiation therapy). Prevention: brca testing....Just to a name a few.

In brief: Alot!

Chemo: molecular staging leading to more precise targeted therapy; new drugs such as Herceptin (trastuzumab) and aromatase inhibitors.
Surgery: increased breast conserving rx, sentinel ln biopsy, oncoplastic surgery, nipple-sparing mastectomy. Radiation therapy: partial breast irradiation (brachytherapy, intraoperative radiation therapy). Prevention: brca testing....Just to a name a few.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
2 comments
Dr. Liawaty Ho
I agree. In addition, risk stratification strategy that is used to guide treatment selection such as - oncotype Dx, adjuvantonline, and soon to come tailorRX.
Dr. Otto Placik
Great summary
Dr. Andrew Turrisi
Radiation Oncology
1 doctor agrees

In brief: By the 1990's...

Breast conservation was proven to be equivalent to mastectomy, and that evidence holds strongly today.
Use of sentinel node, and now limiting node dissetion is new. Knowledge of brca, her-2-neu, trastuzumab (herceptin) are since then. Some women now opt for bilateral mastectomy (+/- reconstruction) despite no change in mortality has currency. Chemo with taxanes and neoadjuvant approaches newer.

In brief: By the 1990's...

Breast conservation was proven to be equivalent to mastectomy, and that evidence holds strongly today.
Use of sentinel node, and now limiting node dissetion is new. Knowledge of brca, her-2-neu, trastuzumab (herceptin) are since then. Some women now opt for bilateral mastectomy (+/- reconstruction) despite no change in mortality has currency. Chemo with taxanes and neoadjuvant approaches newer.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
Thank
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